Article
Metabolic individuality: Limitations, challenges, and potential for clinical utility.
Cell metabolism - 7 Feb 2023
Elsea Sarah H, Posey Jennifer E
Abstract excerpt
In Nature Medicine, Surendran and colleagues recently reported the analysis of human plasma metabolomic data for 913 metabolites in ∼20,000 individuals, identifying 2,599 metabolite-genetic variant associations and >400 metabolite signatures comprised of jointly regulated metabolites. This extensive atlas of variant-metabolite relationships reveals novel genomic mechanisms driving metabolic phenotypes.
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