Article

Histone demethylase UTX regulates glioblastoma progression through affecting periostin expression

2021-12-19

Abstract excerpt

The histone H3K27 demethylase UTX participates in regulating multiple cancer types. However, less is known about the UTX function in glioblastoma (GBM). This study aims to define the effect of UTX on GBM. GEPIA2 database analysis showed that UTX expression was significantly increased in GBM and inversely correlated with survival. Knockdown UTX inhibited GBM cell proliferation, migration, and invasion while promoti...

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Literature Corpus work: b0dc3671-be7c-50cb-ba61-e0b9a5a904ba
DOI: 10.1101/2021.12.17.473115

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