Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MEOX2 homeobox gene promotes growth of malignant gliomas

24 Apr 2022

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) is an aggressive tumor that frequently exhibits gain of chromosome 7, loss of chromosome 10, and aberrantly activated receptor tyrosine kinase signaling pathways. Previously, we identified Mesenchyme Homeobox 2 (MEOX2), a gene located on chromosome 7, as an upregulated transcription factor in GBM. Overexpressed transcription factors can be involved in driving GBM. Here, we aimed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to Glioma Diagnosis and Treatment
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35468210
DOI: 10.1093/neuonc/noac110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MEOX2 homeobox gene promotes growth of malignant gliomasPMID 35468210Read ↗

<i>MEOX2</i> homeobox gene promotes growth of malignant gliomasSemantic proximity Read ↗

Integrated Analysis Identifies MEOX2 as a Malignant Driver and Prognostic Biomarker in Brain GliomaSemantic proximity Read ↗

MEOX2-mediated regulation of Cathepsin S promotes cell proliferation and motility in gliomaSemantic proximity Read ↗

Expression profile and prognostic values of Chromobox family members in human glioblastomaSemantic proximity Read ↗

Transcription Factor ELF1 Activates MEIS1 Transcription and Then Regulates the GFI1/FBW7 Axis to Promote the Development of GliomaSemantic proximity Read ↗

Genetically Engineered Brain Organoids Recapitulate Spatial and Developmental States of Glioblastoma ProgressionSemantic proximity Read ↗

Loss of ELAVL2 is associated with aggressive mesenchymal transition in glioblastomaSemantic proximity Read ↗

Prognostic significance of MEOX2 in gliomasSemantic proximity Read ↗

The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysisSemantic proximity Read ↗

PLEK2, RRM2, GCSH: A Novel WWOX-Dependent Biomarker Triad of Glioblastoma at the Crossroads of Cytoskeleton Reorganization and Metabolism AlterationsSemantic proximity Read ↗

PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion.Semantic proximity Read ↗

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.