Article

Histone demethylase UTX regulates glioblastoma progression through affecting periostin expression

2022-02-21

Abstract excerpt

<title>Abstract</title> <p>The histone H3K27 demethylase UTX participates in regulating multiple cancer types. However, less is known about the function of UTX in glioblastoma (GBM), let alone in glioblastoma stem-like cells (GSCs). Our study aims to investigate the functional role and regulatory mechanism of UTX on GBM. By summarizing data from the TCGA database, we showed that UTX expression was significantly i...

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Literature Corpus work: 26330362-353f-5883-b26e-244bc6a0833d
DOI: 10.21203/rs.3.rs-1299845/v2

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