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Article

E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression

2022-10-10

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM) is the most common malignant glioma with high recurrence rate and a poor prognosis. However, the molecular mechanism of malignant progression of GBM is still unclear. In present study, through proteomic analysis of clinical primary and recurrent glioma samples, we identified that aberrant E3 ligase MAEA expressed in recurrent samples. The results of bioinformatics ana...

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Literature Corpus work
ca760064-a916-54b6-bad2-a08083fa90f1
DOI
10.21203/rs.3.rs-2123722/v1
Open publication

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E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progressionDOI 10.21203/rs.3.rs-2123722/v1
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