Article

FastGxC: Fast and Powerful Context-Specific eQTL Mapping in Bulk and Single-Cell Data

2021-06-18

Abstract excerpt

Context-specific eQTLs mediate genetic risk for complex diseases. However, limitations in current methods for identifying these eQTLs have hindered their comprehensive characterization and downstream interpretation of disease-associated variants. Here, we introduce FastGxC, a method to efficiently and powerfully map context-specific eQTLs by leveraging the correlation structure in genomic studies with repeated sam...

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Literature Corpus work: b098409c-f3b9-5dad-9a0a-9f631b4dd639
DOI: 10.1101/2021.06.17.448889

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