Article
Calculation of IBD probabilities with dense SNP or sequence data.
Genetic epidemiology - 1 Sept 2008
Keith Jonathan M, McRae Allan, Duffy David, Mengersen Kerrie, Visscher Peter M
Abstract excerpt
The probabilities that two individuals share 0, 1, or 2 alleles identical by descent (IBD) at a given genotyped marker locus are quantities of fundamental importance for disease gene and quantitative trait mapping and in family-based tests of association. Until recently, genotyped markers were sufficiently sparse that founder haplotypes could be modelled as having been drawn from a population in linkage...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
