Article
A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics.
Genome research - 1 Jul 2011
Moltke Ida, Albrechtsen Anders, Hansen Thomas V O, Nielsen Finn C, Nielsen Rasmus
Abstract excerpt
All individuals in a finite population are related if traced back long enough and will, therefore, share regions of their genomes identical by descent (IBD). Detection of such regions has several important applications-from answering questions about human evolution to locating regions in the human genome containing disease-causing variants. However, IBD regions can be difficult to detect, especially in the common...
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