Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium.

doi:10.1002/gepi.20378

Article

Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium.

Genetic epidemiology - 1 Apr 2009

Albrechtsen Anders, Sand Korneliussen Thorfinn, Moltke Ida, van Overseem Hansen Thomas, Nielsen Finn Cilius, Nielsen Rasmus

Abstract excerpt

Estimates of relatedness have several applications such as the identification of relatives or in identifying disease related genes through identity by descent (IBD) mapping. Here we present a new method for identifying IBD tracts among individuals from genome-wide single nucleotide polymorphisms...

Topics

Chromosome Mapping
Genome-Wide Association Study
Humans
Linkage Disequilibrium
Markov Chains
Polymorphism, Single Nucleotide

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.