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Article

Efficient identification of identical-by-descent status in pedigrees with many untyped individuals.

Bioinformatics (Oxford, England) - 15 Jun 2010

Li Xin, Yin Xiaolin, Li Jing

Abstract excerpt

MOTIVATION: Inference of identical-by-descent (IBD) probabilities is the key in family-based linkage analysis. Using high-density single nucleotide polymorphism (SNP) markers, one can almost always infer haplotype configurations of each member in a family given all individuals being typed. Consequently, the IBD status can be obtained directly from haplotype configurations. However, in reality, many family members...

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Identifiers

PMID: 20529905
DOI: 10.1093/bioinformatics/btq222
PMCID: PMC2881406

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Source receipt: pubmed, retrieved 7 Sept 2026.

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