Article

Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3

2022-04-15

Abstract excerpt

Streptococcus pneumoniae is a major pathogen in children, elderly subjects and immunodeficient patients. PTX3 is a fluid phase pattern recognition molecule (PRM) involved in resistance to selected microbial agents and in regulation of inflammation. The present study was designed to assess the role of PTX3 in invasive pneumococcal infection. In a murine model of invasive pneumococcal infection, PTX3 was strongly in...

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Literature Corpus work: b06ab098-80cf-5a16-b15f-253c72f2d337
DOI: 10.1101/2022.04.14.488329

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