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Article

The long pentraxin PTX3 as a functional ancestor of antibodies in the immune response to Aspergillus fumigatus

2019-01-01

Abstract excerpt

Invasive aspergillosis (IA) is a life-threatening infection amongst immunocompromised individuals primarily caused by the opportunistic fungus Aspergillus fumigatus (AF). A key role in the early immune response to AF is played by the complement system, an essential component of the humoral arm of innate immunity that includes three distinct activation pathways: classical, lectin and alternative (CP, LP and AP, res...

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Literature Corpus work
51183635-29b3-5d05-852a-4edc6e58575f
DOI
10.21954/ou.ro.0000ec4e
Open publication

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