Article
The Dual Complexity of PTX3 in Health and Disease: A Balancing Act?
Trends in molecular medicine - 1 Jun 2016
Magrini Elena, Mantovani Alberto, Garlanda Cecilia
Abstract excerpt
The humoral arm of innate immunity is complex and includes various molecules that serve as markers of inflammation with complementary characteristics, such as the short pentraxins C-reactive protein (CRP) and serum amyloid P (SAP) and the long pentraxin PTX3. There is a growing amount of evidence - including mouse and human genetics - that suggests that PTX3 is essential in conferring host resistance against...
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