Article
Fine-scale recombination rate differences between sexes, populations and individuals.
Nature - 28 Oct 2010
Kong Augustine, Thorleifsson Gudmar, Gudbjartsson Daniel F, Masson Gisli, Sigurdsson Asgeir, Jonasdottir Aslaug, Walters G Bragi, Jonasdottir Adalbjorg, Gylfason Arnaldur, Kristinsson Kari Th, Gudjonsson Sigurjon A, Frigge Michael L, Helgason Agnar, Thorsteinsdottir Unnur, Stefansson Kari
Abstract excerpt
Meiotic recombinations contribute to genetic diversity by yielding new combinations of alleles. Recently, high-resolution recombination maps were inferred from high-density single-nucleotide polymorphism (SNP) data using linkage disequilibrium (LD) patterns that capture historical recombination events. The use of these maps has been demonstrated by the identification of recombination hotspots and associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.