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Article

Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle.

PLoS genetics - 1 Jan 2012

Sandor Cynthia, Li Wanbo, Coppieters Wouter, Druet Tom, Charlier Carole, Georges Michel

Abstract excerpt

We use >250,000 cross-over events identified in >10,000 bovine sperm cells to perform an extensive characterization of meiotic recombination in male cattle. We map Quantitative Trait Loci (QTL) influencing genome-wide recombination rate, genome-wide hotspot usage, and locus-specific recombination rate. We fine-map three QTL and present strong evidence that genetic variants in REC8 and RNF212 influence genome-wide...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22844258
DOI: 10.1371/journal.pgen.1002854
PMCID: PMC3406008

Genes

PRDM9
REC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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