Article
Construction of PRDM9 allele-specific recombination maps in cattle using large-scale pedigree analysis and genome-wide single sperm genomics.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Apr 2018
Zhou Yang, Shen Botong, Jiang Jicai, Padhi Abinash, Park Ki-Eun, Oswalt Adam, Sattler Charles G, Telugu Bhanu P, Chen Hong, Cole John B, Liu George E, Ma Li
Abstract excerpt
PRDM9 contributes to hybrid sterility and species evolution. However, its role is to be confirmed in cattle, a major domesticated livestock species. We previously found an association near PRDM9 with cattle recombination features, but the causative variants are still unknown. Using millions of genotyped cattle with pedigree information, we characterized five PRDM9 alleles and generated allele-specific...
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