Article

Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro

2021-09-14

Abstract excerpt

New technologies that profile chromatin modifications at single-cell resolution offer enormous promise for functional genomic characterization. However, the sparsity of these measurements and the challenge of integrating multiple binding maps represent significant challenges. Here we introduce scCUT&Tag-pro, a multimodal assay for profiling protein-DNA interactions coupled with the abundance of surface proteins in...

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Literature Corpus work: b0410f65-e844-584b-a8d8-e5d0c15f7205
DOI: 10.1101/2021.09.13.460120

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