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Article

A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.

Molecular cell - 7 Jan 2016

van Galen Peter, Viny Aaron D, Ram Oren, Ryan Russell J H, Cotton Matthew J, Donohue Laura, Sievers Cem, Drier Yotam, Liau Brian B, Gillespie Shawn M, Carroll Kaitlin M, Cross Michael B, Levine Ross L, Bernstein Bradley E

Abstract excerpt

Genome-wide profiling of histone modifications can provide systematic insight into the regulatory elements and programs engaged in a given cell type. However, conventional chromatin immunoprecipitation and sequencing (ChIP-seq) does not capture quantitative information on histone modification levels, requires large amounts of starting material, and involves tedious processing of each individual sample. Here, we...

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Identifiers

PMID: 26687680
DOI: 10.1016/j.molcel.2015.11.003
PMCID: PMC4707994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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