Article

Loss of C3aR induces immune infiltration and inflammatory microbiota in a new spontaneous model of colon cancer

2021-01-19

Abstract excerpt

<h4>ABSTRACT</h4> Several lines of evidence suggest that inflammation plays a pivotal role in the development and progression of colorectal cancer (CRC) and can be unleashed by the loss of innate immunosurveillance. The complement system is a well characterized first line of defense against pathogens and a central component of the immune response. Emerging evidence suggests that complement anaphylatoxin C3a produ...

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Literature Corpus work: afc6f612-eadd-52e7-88e8-a5f05d163251
DOI: 10.1101/2021.01.18.426963

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