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Article

Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3.

Oncogene - 4 Feb 2010

Meunier C, Cai J, Fortin A, Kwan T, Marquis J-F, Turbide C, Van Der Kraak L, Jothy S, Beauchemin N, Gros P

Abstract excerpt

Treatment of mice with the carcinogen azoxymethane (AOM) induces a number of lesions in the colon, including hyperplastic lesions, as well adenomas and carcinomas in situ. Inbred strains of mice show different responses to AOM-induced carcinogenesis. A/J mice are highly susceptible and develop a greater number of hyperplastic lesions and tumors (15-70 tumors per mouse) than resistant C57BL/6J mice (0-6 tumors per...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19915610
DOI: 10.1038/onc.2009.369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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