Article

Accurate, comprehensive gene annotation and ortholog identification across thousands of vertebrate genomes with TOGA2

2026-07-04

Abstract excerpt

Inferring orthologs and annotating coding genes remain central challenges in genomics, evident by the growing gap between assembled and annotated genomes. TOGA (Tool to infer Orthologs from Genome Alignments) addresses this challenge by integrating gene annotation and orthology inference. Here, we present TOGA2, the next generation of TOGA, which substantially improves annotation completeness, accuracy, scalabilit...

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Literature Corpus work: af8142d5-df63-5b58-a15d-57491975a167
DOI: 10.64898/2026.06.30.735536

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