Article

HISAT: Hierarchical Indexing for Spliced Alignment of Transcripts

2014-12-12

Abstract excerpt

HISAT is a new, highly efficient system for alignment of sequences from RNA sequencing experiments that achieves dramatically faster performance than previous methods. HISAT uses a new indexing scheme, hierarchical indexing, which is based on the Burrows-Wheeler transform and the Ferragina-Manzini (FM) index. Hierarchical indexing employs two types of indexes for alignment: (1) a whole-genome FM index to anchor ea...

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Literature Corpus work: cb6b6a16-346b-596a-95c6-dd8f864a7af3
DOI: 10.1101/012591

Open publication

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