Article

Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm

2014-05-31

Abstract excerpt

Model organisms can serve the biological and medical community by enabling the study of conserved gene families and pathways in experimentally-tractable systems. Their use, however, hinges on the ability to reliably identify evolutionary orthologs and paralogs with high accuracy, which can be a great challenge at both small and large evolutionary distances. Here, we present a phylogenomics-based approach for the i...

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Literature Corpus work: 60c53998-22af-585a-8e14-7f4cfc24d874
DOI: 10.1101/005736

Open publication

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