Article
The genetics of SLE: an update in the light of genome-wide association studies.
Rheumatology (Oxford, England) - 1 Nov 2008
Rhodes B, Vyse T J
Abstract excerpt
Understanding the pathogenesis of SLE remains a considerable challenge. Multiple abnormalities of both the innate and adaptive immune system have been described and, furthermore, immunological dysfunction precedes clinical presentation by many years. There is a strong genetic basis to SLE, which means that genetic studies can play a key role in furthering our understanding of this disease. Since susceptibility...
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