Article

Identification of a Gene Signature That Predicts Dependence upon YAP/TAZ-TEAD

2023-12-29

Abstract excerpt

Targeted therapies are effective cancer treatments when accompanied by accurate diagnostic tests that can help identify patients that will respond to those therapies. The YAP/TAZ-TEAD axis is activated and plays a causal role in several cancer types, and TEAD inhibitors are currently in early phase clinical trials in cancer patients. However, mutations that predict YAP/TAZ-TEAD activation are not commonly found in...

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Literature Corpus work: af4c7cd5-e035-5b74-8337-ae83cb3abe97
DOI: 10.20944/preprints202312.2314.v1

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