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Article

Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival.

International journal of cancer - 1 Aug 2015

Yuan Hua, Liu Hongliang, Liu Zhensheng, Zhu Dakai, Amos Christopher I, Fang Shenying, Lee Jeffrey E, Wei Qingyi

Abstract excerpt

Cutaneous melanoma (CM) is the most lethal form of skin cancers. The Hippo pathway controls cell migration, development and sizes of the organs in diverse species, and deregulation of this pathway may affect CM progression and prognosis. Therefore, we hypothesized that genetic variants of Hippo pathway genes might predict survival of CM patients. We used the genotyping data of 1,115 common single nucleotide...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25628125
DOI: 10.1002/ijc.29429
PMCID: PMC4437894

Genes

TEAD1
TEAD4
YAP1
LATS1
LATS2
MST1
SAV1
TEAD2
TEAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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