Article

Deep learning uncovers histological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients

2024-06-14

Abstract excerpt

<h4>Summary</h4> Over the last decade, Hippo signaling has emerged as a major tumor-suppressing pathway. Its dysregulation is associated with abnormal expression of YAP1 and TEAD -family genes. Recent works have highlighted the role of YAP1/TEAD activity in several cancers and its potential therapeutic implications. Therefore, identifying patients with a dysregulated Hippo pathway is key to enhancing treatment...

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Literature Corpus work: bf03033f-8fc8-571a-9f38-6f133cbb4a03
DOI: 10.1101/2024.06.14.598991

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