Article

YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER

2018-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Breast cancer heterogeneity has made it challenging to elucidate shared mechanisms that underpin properties that are critical to their growth in vivo . Here, we interrogate the role of YB-1 protein in the in vivo tumorigenic activity of de novo well as cell line models of human breast cancer. Short-hairpin RNA-mediated knockdown of YB-1 in MDA-MB-231 cells blocked both their local tumour-form...

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Literature Corpus work: af4559c3-1910-5ef5-9cf7-ccabacd8b6a5
DOI: 10.1101/372524

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