Article

Extracellular Vesicles from Senescent Stem Cells: A Converging Nexus Between Aging, Regeneration, and Cancer

2026-05-18

Abstract excerpt

Aging causes exhaustion of stem cells (SCs), loss of regenerative potential, and thereby makes them susceptible to age-related diseases (ARDs), known as cellular senescence. Senescent stem cells (SenSCs) secrete Senescence-Associated Secretory Phenotypes (SASPs) that synergistically exacerbate inflammation. Alongside this, they secrete Senescence-Derived extracellular vesicles (SenEVs) that carry a diverse array o...

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Literature Corpus work: aef9e939-ae8b-527d-8e41-f748993bf81b
DOI: 10.20944/preprints202605.1104.v1

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