Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human ESC‐sEVs alleviate age‐related bone loss by rejuvenating senescent bone marrow‐derived mesenchymal stem cells

10 Aug 2020

Abstract excerpt

Tissue-resident stem cell senescence leads to stem cell exhaustion, which is a major cause of physiological and pathological ageing. Stem cell-derived extracellular vesicles (SC-EVs) have been reported in preclinical studies to possess therapeutic potential for diverse diseases. However, whether SC-EVs can rejuvenate senescent tissue stem cells to prevent age-related disorders still remains unknown. Here, we show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Mesenchymal stem cell research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32944188
DOI: 10.1080/20013078.2020.1800971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human ESC‐sEVs alleviate age‐related bone loss by rejuvenating senescent bone marrow‐derived mesenchymal stem cellsPMID 32944188Read ↗

Cell and Cell-Free Therapies to Counteract Human Premature and Physiological Aging: MSCs Come to LightSemantic proximity Read ↗

Mesenchymal stem cell‐derived extracellular vesicles reduce senescence and extend health span in mouse models of agingSemantic proximity Read ↗

Extracellular Vesicles from Senescent Stem Cells: A Converging Nexus Between Aging, Regeneration, and CancerSemantic proximity Read ↗

Advances in mesenchymal stem cell and exosome-based therapies for aging and age-related diseasesSemantic proximity Read ↗

Small extracellular vesicles produced by homeostatic phenotype BMSC promote bone regeneration by transferring anti-senescent factor JMJD6.Semantic proximity Read ↗

Aging and Mesenchymal Stem Cells: Basic Concepts, Challenges and StrategiesSemantic proximity Read ↗

Young BMSC-derived extracellular vesicles containing lncRNA sponging miR-1843a-5p to regulate Mob3a/YAP axis promote osteogenesis of senescent BMSCsSemantic proximity Read ↗

ESC-sEVs alleviate non-early-stage osteoarthritis progression by rejuvenating senescent chondrocytes via FOXO1A-autophagy axis but not inducing apoptosisSemantic proximity Read ↗

Mechanisms and therapeutic strategies linking mesenchymal stem cells senescence to osteoporosisSemantic proximity Read ↗

Engineering Mesenchymal Stem Cells to Extend Healthspan: Therapeutic Potential, Challenges, and Future SolutionsSemantic proximity Read ↗

Extracellular Vesicles and Hematopoietic Stem Cell Aging.Semantic proximity Read ↗

Microvesicles as Potential Biomarkers for the Identification of Senescence in Human Mesenchymal Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.