Article
The power of proteomics to monitor senescence-associated secretory phenotypes and beyond: toward clinical applications.
Expert review of proteomics - 1 Apr 2020
Basisty Nathan, Kale Abhijit, Patel Sandip, Campisi Judith, Schilling Birgit
Abstract excerpt
INTRODUCTION: Cellular senescence is a rapidly growing field with potential relevance for the treatment of multiple human diseases. In the last decade, cellular senescence and the senescence-associated secretory phenotype (SASP) have emerged as central drivers of aging and many chronic diseases, including cancer, neurodegeneration, heart disease and osteoarthritis. Major efforts are underway to develop drugs that...
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