Article

Exosomes are key regulators of non-cell autonomous communication in senescence

2018-06-27

Abstract excerpt

<h4>SUMMARY</h4> Senescence is a cellular phenotype characterized by an irreversible cell cycle arrest and the secretion of inflammatory proteins, denominated senescence-associated secretory phenotype (SASP). The SASP is important in influencing the behavior of neighboring cells and altering the microenvironment; yet, until now this role has been mainly attributed to soluble factors. Here, we report that extracel...

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Literature Corpus work: 2c723604-3310-5c25-9f35-883347acba23
DOI: 10.1101/356238

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