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Longitudinal Micro-Computed Tomography Detects Onset and Progression of Pulmonary Fibrosis in Conditional <i>Nedd4-2</i> Deficient Mice

2023-09-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease which is usually diagnosed late in advanced stages. Little is known about the subclinical development of IPF. We previously generated a mouse model with conditional Nedd4-2 deficiency ( Nedd4-2 −/− ) that develops IPF-like lung disease. The aim of this study was to characterize the onset and progression of IPF-lik...

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Literature Corpus work
aef0783b-11e2-59da-bd8f-5f200a8e0f40
DOI
10.1101/2023.08.31.555725
Open publication

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Longitudinal Micro-Computed Tomography Detects Onset and Progression of Pulmonary Fibrosis in Conditional <i>Nedd4-2</i> Deficient MiceDOI 10.1101/2023.08.31.555725
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