Persistent alveolar bronchiolization, interstitial fibrosis and impaired lung function post-exercise are features of long-COVID in SARS-CoV-2-Delta variant infected aged hamsters

Abstract excerpt

<title>Abstract</title> <p>Long-term consequences of SARS-CoV-2 infection affect the life quality of millions of people and pose a heavy burden on the public health sector. The underlying causes, pathomechanisms and morphological correlates are still largely unknown and further research in appropriate animal models is needed. The goal of the study was to characterize the trajectory of lung regeneration over a per...

Topics

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• Airway Remodeling
• Congenital Diaphragmatic Hernia Studies
• Lung
• Neonatal Respiratory Health Research
• Phenotype
• Predictive Value of Tests
• Prognosis
• Respiratory Support and Mechanisms

Identifiers and source

Literature Corpus work

b54c8fcf-fd09-5de3-b939-634027dc2fc7

DOI

10.21203/rs.3.rs-4681343/v1