Article

Overexpression of MutS impairs DNA mismatch repair and causes cell division defect in <i>E.coli</i>

2020-10-13

Abstract excerpt

MutS and its homologues, from prokaryotes to humans, recognize and bind to DNA mismatches generated during DNA replication, initiate DNA mismatch repair and ensures 100-200 fold increase in replication fidelity. In E.coli , through post transcriptional regulation, at least three mechanisms mediate decline of MutS intracellular concentrations during stress conditions. To understand the significance of this multifo...

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Literature Corpus work: aed76a7c-ba1f-5197-8c22-d1b89946d699
DOI: 10.1101/2020.10.13.337683

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