Article

A novel histone deacetylase inhibitor-based approach to eliminate microglia and retain astrocyte properties in glial cell culture

2021-11-10

Abstract excerpt

<h4>ABSTRACT</h4> The close association between astrocytes and microglia causes great difficulties to distinguish their individual roles in innate immune responses in central nervous system. Current chemical-based methods to eliminate microglia in glial cell culture introduce various molecular and functional alterations to astrocytes. Here, we describe a novel two-step approach to achieve a complete elimination o...

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Literature Corpus work: aed2d598-3acc-581d-9b0c-fd21a3ecbae0
DOI: 10.1101/2021.11.09.467827

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