Article

Blocking Formation of Neurotoxic Reactive Astrocytes is Beneficial Following Stroke

2023-10-16

Abstract excerpt

Microglia and astrocytes play an important role in the neuroinflammatory response and contribute to both the destruction of neighboring tissue as well as the resolution of inflammation following stroke. These reactive glial cells are highly heterogeneous at both the transcriptomic and functional level. Depending upon the stimulus, microglia and astrocytes mount a complex, and specific response composed of distinct...

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Literature Corpus work: 2e3e2220-a844-5b03-9bd3-cfe060218e15
DOI: 10.1101/2023.10.11.561918

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