Article

DUALISTIC SAHA DOSE-DEPENDENT EFFECTS ON GLIAL-INFLAMMATORY RESPONSE

2024-01-17

Abstract excerpt

<h4>ABSTRACT</h4> Neuroinflammation comprises biochemical and cellular responses of the nervous system to injury, emerging as a central process in many neurological conditions. Although beneficial in nature, over-activation of the immune response may result in the production of neurotoxic factors that exacerbate the disease state. Due to the relevant role of histone acetylation in transcriptional regulation, inhi...

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Literature Corpus work: 021916dd-f774-5f3e-ae9b-2c915d87c99b
DOI: 10.1101/2024.01.16.575689

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