Article

Using Latent Chemical Recognition in an Evolved Periplasmic Binding Protein Family to Diversify Biosensors

2026-08-04

Abstract excerpt

Genetically encoded fluorescent biosensors have gained traction in neuroscience as continuous, reagentless reporters of cellular activity in situ . These sensors, often soluble, can also provide time-resolution in multiple biosensing form factors: benchtop and wearable devices, lyophilized powder tests, and smartphone-based diagnostic tests. These biosensors often take advantage of naturally occurring conformatio...

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Literature Corpus work: aecafdd6-2afa-5580-943c-95dee697d820
DOI: 10.64898/2026.08.04.742673

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