Article

The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

2025-02-17

Abstract excerpt

<h4>Summary</h4> As the only gateway governing nucleocytoplasmic transport, the nuclear pore complex (NPC) maintains fundamental cellular processes and deteriorates with age. However, the study of age-related roles of single NPC components remains challenging owing to the complexity of NPC composition. Here we demonstrate that the master energy sensor, AMPK, post-translationally regulates the abundance of the nuc...

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Literature Corpus work: ae85ac22-91e0-52ff-92b9-2908396bccb0
DOI: 10.1101/2025.02.17.638704

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