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Article

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans.

Nature - 8 Oct 2009

Artal-Sanz Marta, Tavernarakis Nektarios

Abstract excerpt

Marked alterations in cellular energy metabolism are a universal hallmark of the ageing process. The biogenesis and function of mitochondria, the energy-generating organelles in eukaryotic cells, are primary longevity determinants. Genetic or pharmacological manipulations of mitochondrial activity profoundly affect the lifespan of diverse organisms. However, the molecular mechanisms regulating mitochondrial...

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PMID: 19812672
DOI: 10.1038/nature08466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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