Article

The intrinsically disordered N-terminus of SUMO1 is an intramolecular inhibitor of SUMO1 interactions

2024-01-05

Abstract excerpt

<h4>SUMMARY</h4> Ubiquitin-related proteins of the SUMO family are reversibly attached to thousands of proteins in eukaryotic cells. Many SUMO substrates, effectors and enzymes carry short motifs (SIMs) that mediate low affinity interactions with SUMO proteins. How specificity is achieved in target selection, SUMO paralogue choice and SUMO-dependent interactions is largely unknown. A unique but poorly understood...

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Literature Corpus work: ae8593e4-de98-58f3-878a-e851e46aa80f
DOI: 10.1101/2024.01.04.574143

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