Article

Hierarchical length and sequence preferences establish a single major piRNA 3’-end

2021-12-09

Abstract excerpt

<h4>ABSTRACT</h4> PIWI-interacting RNAs (piRNAs) guard germline genomes against the deleterious action of retroviruses and other mobile genetic elements. How piRNAs faithfully discriminate between self and non-self to restrict all mobile elements while sparing essential genes remains a key outstanding question in genome biology. PiRNAs use extensive base-pairing to recognize their targets and variable 3’ends coul...

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Literature Corpus work: 6e41101a-c15c-5fa1-9db9-d35123cb49d5
DOI: 10.1101/2021.12.08.471772

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