Article

Uncovering the Mechanistic Landscape of Regulatory DNA with Deep Learning

2025-10-08

Abstract excerpt

<h4>ABSTRACT</h4> The regulatory genome encodes the logic that governs gene expression, enabling cells to respond to developmental, environmental, and evolutionary cues. This logic arises from complex cis -regulatory mechanisms that integrate transcription factor motifs, their syntactical arrangement, and surrounding sequence context, features that remain challenging to decode. Here, we present SEAM (Systematic...

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Literature Corpus work: c4612d34-b0f6-51ed-a4f6-61c0b8700c2c
DOI: 10.1101/2025.10.07.681052

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