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A <i>nox2</i> / <i>cybb</i> zebrafish mutant with defective neutrophil ROS production displays normal initial neutrophil recruitment to sterile tail injuries

2024-02-03

Abstract excerpt

Reactive oxygen species (ROS) are important effectors and modifiers of the acute inflammatory response, recruiting neutrophils to sites of tissue injury. In turn, neutrophils are both consumers and producers of reactive oxygen species. Stimulated neutrophils generate reactive oxygen species in an oxidative burst through the activity of a multimeric phagocytic NADPH oxidase complex. Mutations in the NOX2/CYBB (pre...

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Literature Corpus work
ae1838f4-86ef-561a-bf35-2082364e6e36
DOI
10.1101/2024.02.02.578645
Open publication

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A <i>nox2</i> / <i>cybb</i> zebrafish mutant with defective neutrophil ROS production displays normal initial neutrophil recruitment to sterile tail injuriesDOI 10.1101/2024.02.02.578645
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