Article

Imaging invasive fungal growth and inflammation in NADPH oxidase-deficient zebrafish

2019-07-16

Abstract excerpt

Neutrophils are primary cells of the innate immune system that generate reactive oxygen species (ROS) and mediate host defense. Deficient phagocyte NADPH oxidase (PHOX) function leads to chronic granulomatous disease (CGD) that is characterized by invasive infections including those by the generally non-pathogenic fungus Aspergillus nidulans . The role of neutrophil ROS in this specific host-pathogen interaction...

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Literature Corpus work: 0f74bce3-15c3-5b8b-b272-6fbe5ad78e39
DOI: 10.1101/703728

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