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Article

Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1).

Genesis (New York, N.Y. : 2000) - 1 Sept 2010

Flaherty John P, Spruce Catrina A, Fairfield Heather E, Bergstrom David E

Abstract excerpt

NADPH oxidase complexes are multiprotein assemblies that generate reactive oxygen species in a variety of mammalian tissues. The canonical phagocytic oxidase consists of a heterodimeric, enzymatic core comprised of the transmembrane proteins, CYBB andCYBA and is regulated, in part, by an "organizing" function of NCF1 and an "activating" activity of NCF2. In contexts outside of the phagocyte, these regulatory...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20645308
DOI: 10.1002/dvg.20655
PMCID: PMC3009462

Genes

NOXA1
NCF1
NCF2
CYBB
NOXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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