Article

Bile acid-mediated activation of hepatic stellate cells and myeloid cell leukemia- 1 triggers hepatocarcinogenesis

2024-08-09

Abstract excerpt

<title>Abstract</title> <p>Objective Activated hepatic stellate cells (HSCs) promote hepatocellular carcinoma (HCC) cell growth and migration. Senescent and cancer-associated fibroblasts express various factors contributing to tumor progression, collectively called the senescence-associated secretory phenotype (SASP). Herein, we investigated the mechanism underlying the bile acid-mediated induction of HSC activa...

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Literature Corpus work: adc4a924-e38e-5755-ab48-ab68d8b4e763
DOI: 10.21203/rs.3.rs-4716083/v1

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