Article

Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

2019-10-25

Abstract excerpt

<h4>SUMMARY</h4> Goal-directed behaviors, complex action sequences that maximize reward, are essential for normal function and are significantly impaired across neuropsychiatric disorders. Despite extensive associations between genetic mutations and these brain disorders, the mechanisms by which candidate genes contribute to goal-directed dysfunction remains unclear, owing to challenges in (1) describing aspects...

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Literature Corpus work: ad925c99-6735-5531-bc9a-acaa964a23b6
DOI: 10.1101/818419

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