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Article

Neurexin1⍺ differentially regulates synaptic efficacy within striatal circuits.

Cell reports - 23 Feb 2021

Davatolhagh M Felicia, Fuccillo Marc V

Abstract excerpt

Mutations in genes essential for synaptic function, such as the presynaptic adhesion molecule Neurexin1α (Nrxn1α), are strongly implicated in neuropsychiatric pathophysiology. As the input nucleus of the basal ganglia, the striatum integrates diverse excitatory projections governing cognitive and motor control, and its impairment may represent a recurrent pathway to disease. Here, we test the functional relevance...

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Identifiers

PMID: 33626349
DOI: 10.1016/j.celrep.2021.108773
PMCID: PMC8071350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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